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Boc-Leu-Arg-Arg-AMC

Overview
Catalog # bs-75300c-1mg
Product Name Boc-Leu-Arg-Arg-AMC
Specifications
Storage Buffer Powder
Storage Condition Stable for 1 year after receipt when stored at -20°C.
Target
Product Information CAS Number: 109358-46-5 (free base)

Molecular formula: C33H52N10O7 . C2H4O2

Molecular weight: 700.8 . 60.1

Purity: >98%

Appearance: Solid lyophilized powder.

Solubility: Soluble in 5% acetic acid.

InChiKey: ZYZDREMHVGIZMZ-NYTZCTPBSA-N

SMILES: Cl.CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC(CCCNC(N)=N)C(=O)NC1=CC2=C(C=C1)C(C)=CC(=O)O2
Description Fluorogenic tri-peptide substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. Substrate for the Kex2 endopeptidase from S. Cervisiae, which has substrate specificity toward the C-terminal side of LR, PR and RR sequences. Can be cleaved by Kallikrein 5 with a P1 site preference for basic residues (R and K). Excitation: 380nm. Emission: 460nm. This substrate is useful for inhibitor screening and kinetic analysis.