Trichostatin A (synthetic)
| Overview | |
| Catalog # | bs-75269c-1mg |
| Product Name | Trichostatin A (synthetic) |
| Specifications | |
| Storage Buffer | Solid |
| Storage Condition | Stable for 3 years after receipt when stored at -20°C. |
| Target | |
| Product Information | CAS Number: 58880-19-6 Molecular formula: C17H22N2O3 Molecular weight: 302.4 Purity: >95% (HPLC) Appearance: Off-white solid. Solubility: Soluble in DMSO, ethanol, methanol, dimethyl formamide, acetonitrile or chloroform. Insoluble in water or hexane. InChiKey: RTKIYFITIVXBLE-QEQCGCAPSA-N SMILES: C[C@H](\C=C(/C)\C=C\C(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C |
| Description | Antibiotic, antifungal and antiprotozoal agent. Potent and reversible, cell permeable inhibitor of class I and II histone deacetylases (HDACs). Anticancer, immunosuppressive, antifibrogenic compound. Induces apoptosis and cell growth arrest at both G1 and G2/M phases. Also inactivates mitotic spindle checkpoint. Enhances the efficacy of anticancer agents that target DNA. Downregulates DNA methyltransferase DNMT1 and affects DNA methylation. Telomerase inhibitor. Smooth muscle cell proliferation inhibitor. Anti-inflammatory and inhibits osteoclastogenesis and bone resorption. Promotes either self-renewal or differentiation of embryonic stem cells. |
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