Enniatin A1

Overview
Catalog #	bs-75243c-1mg
Product Name	Enniatin A1
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 4530-21-6 Molecular formula: C35H61N3O9 Molecular weight: 667.9 Purity: >98% (HPLC) Appearance: White to off-white solid. Solubility: Soluble in DMSO, ethanol, methanol or DMF. Almost insoluble in water. InChiKey: OWUREPXBPJFMOK-CIRFPNLUSA-N SMILES: [H][C@@]1([C@@H](C)CC)N(C)C(=O)[C@H](OC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](OC(=O)[C@]([H])([C@@H](C)CC)N(C)C(=O)[C@H](OC1=O)C(C)C)C(C)C)C(C)C
Description	Cyclohexadepsipeptide mycotoxin. One of four major analogs in the enniatin complex. Commonly found food contaminant in cereals and their products. Ionophore antibiotic. Incorporation into the cell membrane forms dimeric structures that transport monovalent ions across the membrane (especially the mitochondrial membranes) affecting oxidative phosphorylation uncoupling. Anticancer compound. Triggers apoptosis in several cancer cell lines. Induced apoptosis in cancer cells (H4IIE rat hepatoma cells), decreasing the activation of the cell proliferation kinase, ERK (p44/p42) and inhibiting TNF-alpha-induced NF-kappaB activation. Moderate inhibitor of ACAT (acylcoenzyme A:cholesterolacyl transferase). Shown to have a variety of other biological activities such as antifungal, anthelmintic, insecticidal, immunomodulatory and phytotoxic activity.