Vincristine . sulfate

Overview
Catalog #	bs-75215c-5mg
Product Name	Vincristine . sulfate
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at +4°C.
Target
Product Information	CAS Number: 2068-78-2 Molecular formula: C46H56N4O10 . H2SO4 Molecular weight: 825.0 . 98.1 Purity: >98% (HPLC) Appearance: White to light-yellow powder. Solubility: Soluble in water, DMSO or methanol. InChiKey: AQTQHPDCURKLKT-JKDPCDLQSA-N SMILES: OS(O)(=O)=O.[H]C(=O)N1C2=C(C=C(C(OC)=C2)[C@]2(C[C@@H]3C[N@@](C[C@](O)(CC)C3)CCC3=C2NC2=C3C=CC=C2)C(=O)OC)[C@@]23CCN4CC=C[C@@](CC)([C@@H](OC(C)=O)[C@](O)(C(=O)OC)[C@]12[H])[C@@]34[H]
Description	Immunosuppressant. Anticancer compound. Chemotherapeutic agent. Depolymerizes microtubules and irreversibly blocks binding of tubulin to microtubule proteins. Apoptosis inducer and cell cycle inhibitor in G2/M phase. Autophagy inhibitor. Inhibits microtubule-mediated fusion of autophagosome with lysosme. Inducer of IL-1beta production. Activates alone and synergistically together with doxorubicin the NLRP3-inflammasome mediated processing of IL-1beta. Monoamine oxidase (MAO) inhibitor.