Purpuromycin

Overview
Catalog #	bs-75162c-5mg
Product Name	Purpuromycin
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 53969-01-0 Molecular formula: C26H18O13 Molecular weight: 538.4 Purity: >95% (HPLC) Appearance: Red powder. Solubility: Soluble in DMSO, aqueous acetonitrile or ethanol. InChiKey: VGXVKHPGBHVPMW-GWQKEKGPSA-N SMILES: O[C@H]1C[C@@]2(OC3=C(O)C(C(OC(C(OC)=O)=C4)=O)=C4C=C13)CC5=C(O)C(C(C=C(OC)C6=O)=O)=C6C(O)=C5O2
Description	Rubromycin antibiotic. Antibacterial, antifungal and anti-protozoal agent. Active against Gram-positive bacteria, Gram-negative bacteria and fungi. Telomerase inhibitor (IC50=3µM). Protein synthesis inhibitor. Binds tRNAs with high affinity and specifically inhibits aminoacyl-tRNA formation consequent inhibition of protein synthesis in these microorganisms. Inhibits of all tRNA synthetases. Effectively inhibits bacterial translation and translation in eukaryotic cells. Modest inhibitor of retroviral reverse transcriptase.