Latrunculin B

Overview
Catalog #	bs-75032c-500ug
Product Name	Latrunculin B
Specifications
Storage Buffer	Film
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 76343-94-7 Molecular formula: C20H29NO5S Molecular weight: 395.5 Purity: >98% (HPLC) Appearance: Colorless viscous film Solubility: Soluble in DMSO (25mg/ml) or ethanol (25mg/ml). InChiKey: NSHPHXHGRHSMIK-JRIKCGFMSA-N SMILES: C[C@@H](CC[C@@H](O[C@]([C@@]1([H])NC(SC1)=O)(O)C2)C[C@H]2O3)/C=C\CC/C(C)=C\C3=O
Description	Cell permeable marine toxin [1]. Disrupts microfilament-mediated processes [2]. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin [1, 2, 3]. Depolymerizes actin filaments (F-actin) [3]. Less potent than Latrunculin A (Prod. No. bs-75028C). May have fewer unwanted effects than latrunculin A and may be preferred for short-term studies [4, 5]. Acts via a different mechanism than cytochalasins.