DD 03-171

Overview
Catalog #	bs-7199c-10mg-solid
Product Name	DD 03-171
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 991.14 Formula: C55 H62 N10 O8 CAS Number: 2366132-45-6 InChi Key: QBPVFCNYKUENHU-UHFFFAOYSA-N InChi: InChI=1S/C55H62N10O8/c1-34-39(12-10-14-41(34)60-49(68)35-16-20-37(21-17-35)55(2,3)4)43-33-62(5)54(73)48(59-43)58-38-22-18-36(19-23-38)51(70)64-30-28-63(29-31-64)27-9-7-6-8-26-56-46(67)32-57-42-15-11-13-40-47(42)53(72)65(52(40)71)44-24-25-45(66)61-50(44)69/h10-23,33,44,57H,6-9,24-32H2,1-5H3,(H,56,67)(H,58,59)(H,60,68)(H,61,66,69) Smiles: CN1C=C(N=C(NC2C=CC(=CC=2)C(=O)N2CCN(CC2)CCCCCCNC(=O)CNC2C=CC=C3C=2C(=O)N(C2CCC(=O)NC2=O)C3=O)C1=O)C1=CC=CC(NC(=O)C2C=CC(=CC=2)C(C)(C)C)=C1C Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	DD-03-171 is a novel degrader of bruton's tyrosine kinase (btk), potently suppressing signaling and proliferation in cancer cells, reducing tumor burden and extends survival in lymphoma pdx models.