DCLK1-IN-1

Overview
Catalog #	bs-7165c-2mg-solid
Product Name	DCLK1-IN-1
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 527.54 Formula: C26 H28 F3 N7 O2 CAS Number: 2222635-15-4 InChi Key: OQFCHSFVWSLDAO-UHFFFAOYSA-N InChi: InChI=1S/C26H28F3N7O2/c1-33-10-12-35(13-11-33)17-8-9-19(22(14-17)38-3)31-25-30-15-21-23(32-25)34(2)20-7-5-4-6-18(20)24(37)36(21)16-26(27,28)29/h4-9,14-15H,10-13,16H2,1-3H3,(H,30,31,32) Smiles: CN1CCN(CC1)C1=CC(OC)=C(C=C1)NC1=NC2=C(C=N1)N(CC(F)(F)F)C(=O)C1C=CC=CC=1N2C Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	DCLK1-IN-1, also known as OUN35154, is a selective, oral bioavailability in vivo-compatible chemical probe of the doublecortin like kinase 1 (DCLK1 kinase) domain. CLK1-IN-1 inhibits DCLK1 and DCLK2 kinases (IC50: DCLK1=9.5/57.2 nM and DCLK2=31/103 nM in binding and kinase assay, respectively). DCLK1-IN-1 will serve as a versatile tool to study DCLK1 biol. and establish its role in cancer.