AFN-1252

Overview
Catalog #	bs-7129c-10mg-solid
Product Name	AFN-1252
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 375.42 Formula: C22 H21 N3 O3 CAS Number: 620175-39-5 InChi Key: QXTWSUQCXCWEHF-JXMROGBWSA-N InChi: InChI=1S/C22H21N3O3/c1-14-17-5-3-4-6-18(17)28-19(14)13-25(2)21(27)10-7-15-11-16-8-9-20(26)24-22(16)23-12-15/h3-7,10-12H,8-9,13H2,1-2H3,(H,23,24,26)/b10-7+ Smiles: CC1C2C=CC=CC=2OC=1CN(C)C(=O)/C=C/C1C=NC2NC(=O)CCC=2C=1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	AFN-1252, also known as AFN-12520000; API-1252; Debio-1452, is an enoyl-(acyl-carrier protein) reductase fabl inhibitor potentially for the treatment of acute bacterial skin. AFN-1252 exhibits typical MIC(90) values of ≤0·015 μg/ml against diverse clinical isolates of S. aureus, oral absorption, long elimination half-live and efficacy in animal models. AFN-1252 demonstrates a Staphylococcus-specific spectrum of activity.