Avasimibe
Overview | |
Catalog # | bs-7116c-10mg-solid |
Product Name | Avasimibe |
Specifications | |
Storage Buffer | Powder |
Storage Condition | Store in dry, dark place at -20C for 1 year. |
Target | |
Product Information | Molecular Weight: 501.72 Formula: C29 H43 N O4 S CAS Number: 166518-60-1 InChi Key: PTQXTEKSNBVPQJ-UHFFFAOYSA-N InChi: InChI=1S/C29H43NO4S/c1-17(2)22-14-25(20(7)8)27(26(15-22)21(9)10)16-28(31)30-35(32,33)34-29-23(18(3)4)12-11-13-24(29)19(5)6/h11-15,17-21H,16H2,1-10H3,(H,30,31) Smiles: CC(C)C1=CC(=CC(C(C)C)=C1CC(=O)NS(=O)(=O)OC1C(=CC=CC=1C(C)C)C(C)C)C(C)C Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power. Shelf Life: 1.0 years |
Description | Avasimibe is an acyl coenzyme A: cholesterol acyltransferase (ACAT) inhibitor. Avasimibe can also reduce the synthesis and secretion of Apo B 100 in HepG2 cells. Avasimibe encapsulated in human serum albumin blocks cholesterol esterification for selective cancer treatment. Avasimibe could be an efficient therapy in the treatment of glioblastoma. |