LQZ-7I

Overview
Catalog #	bs-7113c-10mg-solid
Product Name	LQZ-7I
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 348.35 Formula: C20 H14 F2 N4 CAS Number: 195822-23-2 InChi Key: DKPCKOKYSVPFEB-UHFFFAOYSA-N InChi: InChI=1S/C20H14F2N4/c21-13-5-9-15(10-6-13)23-19-20(24-16-11-7-14(22)8-12-16)26-18-4-2-1-3-17(18)25-19/h1-12H,(H,23,25)(H,24,26) Smiles: FC1C=CC(=CC=1)NC1=NC2=CC=CC=C2N=C1NC1C=CC(F)=CC=1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	LQZ-7I is a malarial protease PfSUB1 inhibitor. LQZ-7I showed significantly improved activity and is the focus of this work. LQZ-7 when given orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors. The data obtained utilizing LQZ-7I in both in vitro and in vivo studies highlights its potential as a lead for further development, which may yield a potential cancer therapeutic by targeting the survivin protein directly.