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Bexarotene

Overview
Catalog # bs-7095c-10mg-solid
Product Name Bexarotene
Specifications
Storage Buffer Powder
Storage Condition Store in dry, dark place at -20C for 1 year.
Target
Product Information Molecular Weight: 348.48

Formula: C24 H28 O2

CAS Number: 153559-49-0

InChi Key: NAVMQTYZDKMPEU-UHFFFAOYSA-N

InChi: InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26)

Smiles: CC1=CC2=C(C=C1C(=C)C1C=CC(=CC=1)C(O)=O)C(C)(C)CCC2(C)C

Purity: 98.0

Solubility: Soluble in DMSO, not in water

Appearance: Solid Power.

Shelf Life: 1.0 years
Description Bexarotene, also known as LGD-1069, is a synthetic retinoic acid agent with potential antineoplastic, chemopreventive, teratogenic and embryotoxic properties. Bexarotene selectively binds to and activates retinoid X receptors (RXRs), thereby inducing changes in gene expression that lead to cell differentiation, decreased cell proliferation, apoptosis of some cancer cell types, and tumor regression.