LIN28 inhibitor LI71
Overview | |
Catalog # | bs-7073c-10mg-solid |
Product Name | LIN28 inhibitor LI71 |
Specifications | |
Storage Buffer | Powder |
Storage Condition | Store in dry, dark place at -20C for 1 year. |
Target | |
Product Information | Molecular Weight: 335.4 Formula: C21 H21 N O3 CAS Number: 1357248-83-9 InChi Key: QWJMABCFVYELBB-GJYPPUQNSA-N InChi: InChI=1S/C21H21NO3/c1-2-25-18-8-4-7-17-15-5-3-6-16(15)19(22-20(17)18)13-9-11-14(12-10-13)21(23)24/h3-5,7-12,15-16,19,22H,2,6H2,1H3,(H,23,24)/t15-,16+,19+/m1/s1 Smiles: CCOC1=CC=CC2[C@@H]3C=CC[C@@H]3[C@@H](NC=21)C1C=CC(=CC=1)C(O)=O Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years |
Description | LIN28 inhibitor LI71 is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation. LIN28 inhibitor LI71 binds the cold shock domain to suppress LIN28's activity against let-7 in leukemia cells and embryonic stem cells. . |