CX-6258

Overview
Catalog #	bs-7067c-10mg-solid
Product Name	CX-6258
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 461.94 Formula: C26 H24 Cl N3 O3 CAS Number: 1202916-90-2 InChi Key: KGBPLKOPSFDBOX-CJLVFECKSA-N InChi: InChI=1S/C26H24ClN3O3/c1-29-10-3-11-30(13-12-29)26(32)18-5-2-4-17(14-18)24-9-7-20(33-24)16-22-21-15-19(27)6-8-23(21)28-25(22)31/h2,4-9,14-16H,3,10-13H2,1H3,(H,28,31)/b22-16+ Smiles: CN1CCCN(CC1)C(=O)C1C=C(C=CC=1)C1=CC=C(/C=C2\C3=CC(Cl)=CC=C3NC\2=O)O1 Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power. Shelf Life: 1.0 years
Description	CX-6258 is a pan-Pim kinases inhibitor with excellent biochemical potency and kinase selectivity. CX-6258 exhibited in vitro synergy with chemotherapeutics and robust in vivo efficacy in two Pim kinases driven tumor models. Inhibition of Pim kinases is expected to have a beneficial effect as cancer therapy.