BAY-876

Overview
Catalog #	bs-7065c-10mg-solid
Product Name	BAY-876
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 496.42 Formula: C24 H16 F4 N6 O2 CAS Number: 1799753-84-6 InChi Key: BKLJDIJJOOQUFG-UHFFFAOYSA-N InChi: InChI=1S/C24H16F4N6O2/c1-12-20(21(24(26,27)28)33-34(12)11-14-4-2-13(10-29)3-5-14)32-23(36)17-9-19(22(30)35)31-18-8-15(25)6-7-16(17)18/h2-9H,11H2,1H3,(H2,30,35)(H,32,36) Smiles: CC1=C(NC(=O)C2=CC(=NC3=CC(F)=CC=C32)C(N)=O)C(=NN1CC1C=CC(=CC=1)C#N)C(F)(F)F Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	BAY-876 is a potent and Selective GLUT1 Inhibitor. BAY-876 showed good metabolic stability in vitro and high oral bioavailability in vivo. GLUT1 overexpression has been reported in many types of human cancers, including those of brain,6 breast, colon, kidney, lung, ovary, and prostate, and is correlated with advanced cancer stages and poor clinical outcomes.