FG-2216

Overview
Catalog #	bs-7033c-10mg-solid
Product Name	FG-2216
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 280.66 Formula: C12 H9 Cl N2 O4 CAS Number: 223387-75-5 InChi Key: OUQVKRKGTAUJQA-UHFFFAOYSA-N InChi: InChI=1S/C12H9ClN2O4/c13-11-7-4-2-1-3-6(7)10(18)9(15-11)12(19)14-5-8(16)17/h1-4,18H,5H2,(H,14,19)(H,16,17) Smiles: OC(=O)CNC(=O)C1N=C(Cl)C2=CC=CC=C2C=1O Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power. Shelf Life: 1.0 years
Description	FG-2216, also known as YM311, is orally bioavailable HIF-prolyl hydroxylase inhibitor. FG-2216 induced significant and reversible Epo induction in vivo. FG-2216 showed the ability to stabilize HIF-α, to stimulate EPO secretion in in vitro studies, and to increase hematocrit, red blood cell count, and hemoglobin levels in an animal efficacy study.