Z433927330

Overview
Catalog #	bs-6993c-10mg-solid
Product Name	Z433927330
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 364.4 Formula: C20 H20 N4 O3 CAS Number: 1005883-72-6 InChi Key: KQUKHINHCUELQL-UHFFFAOYSA-N InChi: InChI=1S/C20H20N4O3/c1-2-27-19(25)16-6-8-17(9-7-16)23-20(26)21-14-15-4-10-18(11-5-15)24-13-3-12-22-24/h3-13H,2,14H2,1H3,(H2,21,23,26) Smiles: CCOC(=O)C1C=CC(=CC=1)NC(=O)NCC1C=CC(=CC=1)N1C=CC=N1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	Z433927330 is a potent and selective aquaporin-7 (AQP7) inhibitor. Z433927330 is also a partial AQP3 inhibitor (IC50, ∼0.7-0.9 μm) and a potent and efficacious inhibitor of mouse AQP7 water permeability (IC50, ∼0.2 μm). Moreover, Z433927330 blocked aquaglyceroporin H2O2 permeability.