Triptonide

Overview
Catalog #	bs-6944c-10mg-solid
Product Name	Triptonide
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 358.39 Formula: C20 H22 O6 CAS Number: 38647-11-9 InChi Key: SWOVVKGLGOOUKI-ZHGGVEMFSA-N InChi: InChI=1S/C20H22O6/c1-8(2)18-13(25-18)14-20(26-14)17(3)5-4-9-10(7-23-15(9)21)11(17)6-12-19(20,24-12)16(18)22/h8,11-14H,4-7H2,1-3H3/t11-,12-,13-,14-,17-,18-,19+,20+/m0/s1 Smiles: C[C@]12CCC3=C(COC3=O)[C@@H]1C[C@@H]1O[C@]31C(=O)[C@]1(O[C@H]1[C@@H]1O[C@]231)C(C)C Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	Triptonide is a Wnt/β-catenin inhibitor. Triptonide can effectively inhibit canonical Wnt/β-catenin signaling by targeting the downstream C-terminal transcription domain of β-catenin or a nuclear component associated with β-catenin. It also effectively induced apoptosis of Wnt-dependent cancer cells, supporting the therapeutic potential of triptonide.