SKL2001

Overview
Catalog #	bs-6923c-10mg-solid
Product Name	SKL2001
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 286.29 Formula: C14 H14 N4 O3 CAS Number: 909089-13-0 InChi Key: PQXINDBPUDNMPE-UHFFFAOYSA-N InChi: InChI=1S/C14H14N4O3/c19-14(16-4-2-6-18-7-5-15-10-18)11-9-13(21-17-11)12-3-1-8-20-12/h1,3,5,7-10H,2,4,6H2,(H,16,19) Smiles: O=C(NCCCN1C=NC=C1)C1C=C(ON=1)C1=CC=CO1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	SKL2001 is a novel agonist of Wnt/β-catenin signaling pathway. SKL2001 suppresses colon cancer spheroid growth through regulation of the E-cadherin/β-Catenin complex. SKL2001 inhibited proliferation of colon cancer cells cultured in 3D spheroid and induced them accumulation in the G0/G1 phase of the cell cycle with a reduced c-myc level.