LDN193189 Tetrahydrochloride

Overview
Catalog #	bs-6899c-10mg-solid
Product Name	LDN193189 Tetrahydrochloride
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 552.33 Formula: C25 H26 Cl4 N6 CAS Number: 2310134-98-4 InChi Key: NYHXPFHFIMRKDS-UHFFFAOYSA-N InChi: InChI=1S/C25H22N6.4ClH/c1-2-4-24-22(3-1)21(9-10-27-24)23-16-29-31-17-19(15-28-25(23)31)18-5-7-20(8-6-18)30-13-11-26-12-14-30;;;;/h1-10,15-17,26H,11-14H2;4*1H Smiles: Cl.Cl.Cl.Cl.C1CNCCN1C1C=CC(=CC=1)C1=CN2N=CC(=C2N=C1)C1=CC=NC2=CC=CC=C21 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	LDN193189 Tetrahydrochloride is a selective BMP type I receptor inhibitor, which efficiently inhibits ALK2 and ALK3 (IC50=5 nM and 30 nM, respectively), with weaker effects on ALK4, ALK5 and ALK7 (IC50≥500 nM).