Trimethylamine N-oxide
| Overview | |
| Catalog # | bs-6879c-10mg-solid |
| Product Name | Trimethylamine N-oxide |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Store in dry, dark place at -20C for 1 year. |
| Target | |
| Product Information | Molecular Weight: 75.11 Formula: C3 H9 N O CAS Number: 1184-78-7 InChi Key: UYPYRKYUKCHHIB-UHFFFAOYSA-N InChi: InChI=1S/C3H9NO/c1-4(2,3)5/h1-3H3 Smiles: C[N+](C)(C)[O-] Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years |
| Description | Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway. |
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