CGP60474

Overview
Catalog #	bs-6799c-10mg-solid
Product Name	CGP60474
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 355.82 Formula: C18 H18 Cl N5 O CAS Number: 164658-13-3 InChi Key: IYNDTACKOAXKBJ-UHFFFAOYSA-N InChi: InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(12-14)23-18-22-9-6-16(24-18)13-5-8-21-17(11-13)20-7-2-10-25/h1,3-6,8-9,11-12,25H,2,7,10H2,(H,20,21)(H,22,23,24) Smiles: OCCCNC1C=C(C=CN=1)C1C=CN=C(NC2=CC(Cl)=CC=C2)N=1 Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power. Shelf Life: 1.0 years
Description	CGP60474 is a potent dual cdk1/cdk2 inhibitor (IC50 values are 20 and 50 nM, respectively). Also displays low micromolar activity at PKCα. Displays reversible G1/S cell cycle arrest in U2-OS cells.