Molidustat

Overview
Catalog #	bs-6679c-10mg-solid
Product Name	Molidustat
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 314.3 Formula: C13 H14 N8 O2 CAS Number: 1154028-82-6 InChi Key: IJMBOKOTALXLKS-UHFFFAOYSA-N InChi: InChI=1S/C13H14N8O2/c22-13-10(20-2-1-16-18-20)8-17-21(13)12-7-11(14-9-15-12)19-3-5-23-6-4-19/h1-2,7-9,17H,3-6H2 Smiles: O=C1C(=CNN1C1C=C(N=CN=1)N1CCOCC1)N1C=CN=N1 Purity: 98.0 Solubility: Soluble in DMSO, DMF, and 1:1 DMF:PBS Appearance: Solid Power. Shelf Life: 1.0 years
Description	Molidustat, also known as BAY 85-3934, is a novel inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase (PH) which stimulates erythropoietin (EPO) production and the formation of red blood cells. Phase I data have shown that inhibition of HIF-PH by Molidustat results in an increase in endogenous production of EPO. Molidustat is currently clinical trials at Bayer for the treatment of patients suffering from renal anemia due to chronic kidney disease.