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Bardoxolone

Overview
Catalog # bs-6639c-10mg-solid
Product Name Bardoxolone
Specifications
Storage Buffer Powder
Storage Condition Store in dry, dark place at -20C for 1 year.
Target
Product Information Molecular Weight: 491.66

Formula: C31 H41 N O4

CAS Number: 218600-44-3

InChi Key: TXGZJQLMVSIZEI-UQMAOPSPSA-N

InChi: InChI=1S/C31H41NO4/c1-26(2)10-12-31(25(35)36)13-11-30(7)23(19(31)16-26)20(33)14-22-28(5)15-18(17-32)24(34)27(3,4)21(28)8-9-29(22,30)6/h14-15,19,21,23H,8-13,16H2,1-7H3,(H,35,36)/t19-,21-,23-,28-,29+,30+,31-/m0/s1

Smiles: CC1(C)C[C@H]2[C@H]3C(=O)C=C4[C@@]5(C)C=C(C#N)C(=O)C(C)(C)[C@@H]5CC[C@@]4(C)[C@]3(C)CC[C@]2(CC1)C(O)=O

Purity: 98.0

Solubility: Soluble in DMSO

Appearance: Solid Power.

Shelf Life: 1.0 years
Description Bardoxolone, also known as RTA-401 and CDDO, is a synthetic oleanane triterpenoid. Bardoxolone blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM.