JNJ-63533054

Overview
Catalog #	bs-6616c-10mg-solid
Product Name	JNJ-63533054
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 316.78 Formula: C17 H17 Cl N2 O2 CAS Number: 1802326-66-4 InChi Key: MWDVCHRYCKXEBY-LBPRGKRZSA-N InChi: InChI=1S/C17H17ClN2O2/c1-12(13-6-3-2-4-7-13)20-16(21)11-19-17(22)14-8-5-9-15(18)10-14/h2-10,12H,11H2,1H3,(H,19,22)(H,20,21)/t12-/m0/s1 Smiles: C[C@H](NC(=O)CNC(=O)C1=CC(Cl)=CC=C1)C1C=CC=CC=1 Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power. Shelf Life: 1.0 years
Description	JNJ 63533054 is a potent and selective GPR139 agonist (EC50 = 16 nM) that is brain and cell penetrant. JNJ 63533054 is selective for GPR139 over a panel of GPCRs, ion channels and transporters, including GPR142 and is orally bioavailable.