GSK-872

Overview
Catalog #	bs-6592c-10mg-solid
Product Name	GSK-872
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 383.49 Formula: C19 H17 N3 O2 S2 CAS Number: 1346546-69-7 InChi Key: ZCDBTQNFAPKACC-UHFFFAOYSA-N InChi: InChI=1S/C19H17N3O2S2/c1-12(2)26(23,24)14-4-5-16-15(10-14)17(7-8-20-16)22-13-3-6-19-18(9-13)21-11-25-19/h3-12H,1-2H3,(H,20,22) Smiles: CC(C)S(=O)(=O)C1C=C2C(=CC=NC2=CC=1)NC1=CC2N=CSC=2C=C1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power Shelf Life: 1.0 years
Description	GSK-872 is a receptor-interacting protein kinase-3 (RIP3) inhibitor. GSK-872 inhibits TNF- and virus-induced necrosis in 3T3-SA fibroblasts. It also inhibits necrosis induced by toll-like receptor 3 (TLR3).