NCB-0846

Overview
Catalog #	bs-6496c-2mg-solid
Product Name	NCB-0846
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 375.42 Formula: C21 H21 N5 O2 CAS Number: 1792999-26-8 InChi Key: FYWRWBSYRGSWIQ-IYBDPMFKSA-N InChi: InChI=1S/C21H21N5O2/c27-15-5-7-16(8-6-15)28-19-3-1-2-13-11-22-21(26-20(13)19)25-14-4-9-17-18(10-14)24-12-23-17/h1-4,9-12,15-16,27H,5-8H2,(H,23,24)(H,22,25,26)/t15-,16+ Smiles: O[C@@H]1CC[C@@H](CC1)OC1C=CC=C2C=NC(NC3C=CC4N=CNC=4C=3)=NC2=1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power Shelf Life: 1.0 years
Description	NCB-0846 is the first orally available small-molecule TNIK inhibitor, having anti-Wnt activity and suppressing Wnt-driven intestinal tumorigenesis, also inhibiting FLT3, JAK3, PDGFRa, TRKA, CDK2/CycA2, and HGK.