Vacquinol-1

Overview
Catalog #	bs-6454c-10mg-solid
Product Name	Vacquinol-1
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 352.86 Formula: C21 H21 Cl N2 O CAS Number: 5428-80-8 InChi Key: VKLJPGAHSLIQKH-UHFFFAOYSA-N InChi: InChI=1S/C21H21ClN2O/c22-15-10-8-14(9-11-15)20-13-17(16-5-1-2-6-18(16)24-20)21(25)19-7-3-4-12-23-19/h1-2,5-6,8-11,13,19,21,23,25H,3-4,7,12H2 Smiles: OC(C1CCCCN1)C1=CC(=NC2=CC=CC=C12)C1=CC=C(Cl)C=C1 Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power Shelf Life: 1.0 years
Description	Vacquinol-1, also known as NSC 13316, is an activator of MKK4-dependent macropinocytotic cell death in glioblastoma cells. Vacquinol-1 has beneficial effects on a glioblastoma multiforme mouse model by oral administration. In glioblastoma cells, Vacquinol-1 targets macropinocytosis, a cellular process that will not lead to cell death in normal cells.