PD158780
Overview | |
Catalog # | bs-6424c-10mg-solid |
Product Name | PD158780 |
Specifications | |
Storage Buffer | Powder |
Storage Condition | Store in dry, dark place at -20C for 1 year. |
Target | |
Product Information | Molecular Weight: 330.18 Formula: C14 H12 Br N5 CAS Number: 171179-06-9 InChi Key: KFHMLBXBRCITHF-UHFFFAOYSA-N InChi: InChI=1S/C14H12BrN5/c1-16-13-6-11-12(7-17-13)18-8-19-14(11)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20) Smiles: CNC1=CC2C(NC3=CC(Br)=CC=C3)=NC=NC=2C=N1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power Shelf Life: 1.0 years |
Description | PD 158780 is a potent in vitro inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) (IC50 0.08 nM), and other members of the erbB family, by competitive binding at the ATP site of these signal transduction enzymes. |