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(-)-JQ-1

Overview
Catalog # bs-6414c-2mg-solid
Product Name (-)-JQ-1
Specifications
Storage Buffer Powder
Storage Condition Store in dry, dark place at -20C for 1 year.
Target
Product Information Molecular Weight: 456.99

Formula: C23 H25 Cl N4 O2 S

CAS Number: 1268524-71-5

InChi Key: DNVXATUJJDPFDM-QGZVFWFLSA-N

InChi: InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m1/s1

Smiles: CC1=NN=C2[C@@H](CC(=O)OC(C)(C)C)N=C(C3=C(SC(C)=C3C)N12)C1C=CC(Cl)=CC=1

Purity: 98.0

Solubility: ≥ 22.8mg/mL in DMSO, ≥ 46.9 mg/mL in EtOH with ultrasonic

Appearance: Solid Power

Shelf Life: 1.0 years
Description (-)-JQ-1 is the stereoisomer of (+)-JQ1. (+)-JQ1 potently decreases expression of both BRD4 target genes, whereas (-)-JQ-1 Enantiomer has no effect.