BI-9564, BRD9 Bromodomain Inhibitor

Overview
Catalog #	bs-60323c-2-mg-solid
Product Name	BI-9564, BRD9 Bromodomain Inhibitor
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 353.41 Formula: C20 H23 N3 O3 CAS Number: 1883429-22-8 InChi Key: BJFSUDWKXGMUKA-UHFFFAOYSA-N InChi: InChI=1S/C20H23N3O3/c1-22(2)11-13-8-19(26-5)15(9-18(13)25-4)17-12-23(3)20(24)16-10-21-7-6-14(16)17/h6-10,12H,11H2,1-5H3 Smiles: CN(C)CC1=CC(OC)=C(C=C1OC)C1=CN(C)C(=O)C2=CN=CC=C21 Purity: 98.0 Solubility: DMSO up to 100 mM Appearance: Solid Power. Shelf Life: 1.0 years
Description	BI-9564 is a potent and selective inhibitor of BRD9 and BRD7 bromodomains (Kds = 14.1 and 239 nM; IC50s = 75 nM and 3.4 µM, respectively). BI-9564 is useful in further exploring BRD9 bromodomain biology in both in vitro and in vivo settings. Selective inhibitors of bromodomain-containing protein 9 (BRD9) may have therapeutic potential in the treatment of human malignancies and inflammatory diseases.