UNC2327, Allosteric PRMT3 Inhibitor
| Overview | |
| Catalog # | bs-60253c-2-mg-solid |
| Product Name | UNC2327, Allosteric PRMT3 Inhibitor |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Store in dry, dark place at -20C for 1 year. |
| Target | |
| Product Information | Molecular Weight: 319.38 Formula: C14 H17 N5 O2 S CAS Number: 1426152-53-5 InChi Key: MYTRGTBDVGKKRO-UHFFFAOYSA-N InChi: InChI=1S/C14H17N5O2S/c20-13(19-6-2-1-3-7-19)9-15-14(21)16-10-4-5-11-12(8-10)22-18-17-11/h4-5,8H,1-3,6-7,9H2,(H2,15,16,21) Smiles: O=C(CNC(=O)NC1=CC2SN=NC=2C=C1)N1CCCCC1 Purity: 98.0 Solubility: DMSO up to 100 mM Appearance: Solid Power. Shelf Life: 1.0 years |
| Description | UNC2327 is a potent and selective allosteric protein arginine methyltransferase 3 (PRMT3) inhibitor with IC50 ~ 230 nM. It occupies a novel allosteric binding site and is noncompetitive with both the peptide substrate and cofactor. |
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