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THZ1 --- Covalent CDK7 Inhibitor

Overview
Catalog # bs-60214c-2-mg-solid
Product Name THZ1 --- Covalent CDK7 Inhibitor
Specifications
Storage Buffer Powder
Storage Condition Store in dry, dark place at -20C for 1 year.
Target
Product Information Molecular Weight: 566.05

Formula: C31 H28 Cl N7 O2

CAS Number: 1604810-83-4

InChi Key: OBJNFLYHUXWUPF-IZZDOVSWSA-N

InChi: InChI=1S/C31H28ClN7O2/c1-39(2)16-6-11-28(40)35-21-14-12-20(13-15-21)30(41)36-22-7-5-8-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-10-4-3-9-24(25)27/h3-15,17-19,33H,16H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b11-6+

Smiles: CN(C)C/C=C/C(=O)NC1C=CC(=CC=1)C(=O)NC1=CC(=CC=C1)NC1N=C(C(Cl)=CN=1)C1=CNC2=CC=CC=C21

Purity: 98.0

Solubility: DMSO up to 50 mM

Appearance: Solid Power.

Shelf Life: 1.0 years
Description THZ1 is a novel potent, selective and cell permeable irreversible CDK7 inhibitor with an IC50 ~3.2 nM.