FH1 --- Hepatocytes Functional Enhancer

Overview
Catalog #	bs-60127c-2-mg-solid
Product Name	FH1 --- Hepatocytes Functional Enhancer
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 282.34 Formula: C17 H18 N2 O2 CAS Number: 2719-05-3 InChi Key: OEXMNSOPAKOPEF-UHFFFAOYSA-N InChi: InChI=1S/C17H18N2O2/c1-12(20)18-16-7-3-14(4-8-16)11-15-5-9-17(10-6-15)19-13(2)21/h3-10H,11H2,1-2H3,(H,18,20)(H,19,21) Smiles: CC(=O)NC1C=CC(CC2C=CC(=CC=2)NC(C)=O)=CC=1 Purity: 98.0 Solubility: DMSO up to 100 mM Appearance: Solid Power. Shelf Life: 1.0 years
Description	FH1 is a potent and selective small molecule that enhances hepatocyte functions and promotes the differentiation and maturation of iPSC-derived hepatocytes toward a more mature phenotype in vitro. FH1 was identified by a high-throughput, cell-based screening using primary human hepatocytes. It was added to the basal medium with or without OSM on day 21 after the initiation of differentiation of iPSCs and acted over a period of 9 day to promote more pronounced hepatocyte morphologies, including polygonal cell shapes, visible nuclei and more noticeable bile canaliculi between hepatocytes.