PS48 --- PDK1 Activator
| Overview | |
| Catalog # | bs-60026c-5-mg-solid |
| Product Name | PS48 --- PDK1 Activator |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Store in dry, dark place at -20C for 1 year. |
| Target | |
| Product Information | Molecular Weight: 286.75 Formula: C17 H15 Cl O2 CAS Number: 1180676-32-7 InChi Key: LLJYFDRQFPQGNY-QINSGFPZSA-N InChi: InChI=1S/C17H15ClO2/c18-16-10-7-13(8-11-16)6-9-15(12-17(19)20)14-4-2-1-3-5-14/h1-5,7-8,10-12H,6,9H2,(H,19,20)/b15-12- Smiles: OC(=O)C=C(CCC1C=CC(Cl)=CC=1)C1C=CC=CC=1 Purity: 98.0 Solubility: DMSO up to 100 mM Appearance: Solid Power. Shelf Life: 1.0 years |
| Description | PS48 is a novel PDK1 (phosphoinositide-dependent protein kinase 1) activator (Kd = 10.3 μM), which binds to the HM/PIF binding pocket rather than the ATP-binding site. PS48 has been used to enhance iPSC reprogramming from human epidermal keratinocytes and endothelial cells. |
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