Hh-Ag1.5 --- Hedgehog Agonist
| Overview | |
| Catalog # | bs-60004c-2-mg-solid |
| Product Name | Hh-Ag1.5 --- Hedgehog Agonist |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Store in dry, dark place at -20C for 1 year. |
| Target | |
| Product Information | Molecular Weight: 526.04 Formula: C28 H26 Cl F2 N3 O S CAS Number: 612542-14-0 InChi Key: RXZDWPYJFCAZCW-MEMLXQNLSA-N InChi: InChI=1S/C28H26ClF2N3OS/c1-32-20-5-7-21(8-6-20)34(16-17-3-2-4-19(15-17)18-11-13-33-14-12-18)28(35)27-25(29)24-22(30)9-10-23(31)26(24)36-27/h2-4,9-15,20-21,32H,5-8,16H2,1H3/t20-,21- Smiles: CN[C@@H]1CC[C@H](CC1)N(CC1C=C(C=CC=1)C1C=CN=CC=1)C(=O)C1SC2=C(C=1Cl)C(F)=CC=C2F Purity: 98.0 Solubility: DMSO up to 50 mM Appearance: Solid Power. Shelf Life: 1.0 years |
| Description | Hh-Ag1.5 is one of the most potent and selective small-molecule agonists of the Hedgehog pathway, targeting Smoothened (Smo) with an EC50 ~1 nM. Studies showed that it has more potent activity than the recombinant Hh protein in activating Smo and hedgehog pathway. |
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