Tasisulam(LY573636)
Overview | |
Catalog # | bs-1090c-10mg-solid |
Product Name | Tasisulam(LY573636) |
Specifications | |
Storage Buffer | Powder |
Storage Condition | Store in dry, dark place at -20C for 1 year. |
Target | |
Product Information | Molecular Weight: 415.11 Formula: C11 H6 Br Cl2 N O3 S2 CAS Number: 519055-62-0 InChi Key: WWONFUQGBVOKOF-UHFFFAOYSA-N InChi: InChI=1S/C11H6BrCl2NO3S2/c12-9-3-4-10(19-9)20(17,18)15-11(16)7-2-1-6(13)5-8(7)14/h1-5H,(H,15,16) Smiles: O=C(NS(=O)(=O)C1=CC=C(Br)S1)C1C=CC(Cl)=CC=1Cl Purity: 98.0 Solubility: DMSO: 77 mg/mL (185.5 mM) Ethanol: 77 mg/mL (185.5 mM) Water: <1 mg/mL Appearance: Solid Power Shelf Life: 1.0 years |
Description | Tasisulam, also known as LY573636, is an acyl-sulfonamide with potential antineoplastic activity. Selectively toxic towards tumor cells, tasisulam appears to induce tumor cell apoptosis by a mitochondrial-targeted mechanism involving the loss of mitochondrial membrane potential and induction of reactive oxygen species (ROS). In combination with an angiogenesis inhibitor, this agent may exhibit synergistic antiangiogenic activity. |