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Tasisulam(LY573636)

Overview
Catalog # bs-1090c-10mg-solid
Product Name Tasisulam(LY573636)
Specifications
Storage Buffer Powder
Storage Condition Store in dry, dark place at -20C for 1 year.
Target
Product Information Molecular Weight: 415.11

Formula: C11 H6 Br Cl2 N O3 S2

CAS Number: 519055-62-0

InChi Key: WWONFUQGBVOKOF-UHFFFAOYSA-N

InChi: InChI=1S/C11H6BrCl2NO3S2/c12-9-3-4-10(19-9)20(17,18)15-11(16)7-2-1-6(13)5-8(7)14/h1-5H,(H,15,16)

Smiles: O=C(NS(=O)(=O)C1=CC=C(Br)S1)C1C=CC(Cl)=CC=1Cl

Purity: 98.0

Solubility: DMSO: 77 mg/mL (185.5 mM) Ethanol: 77 mg/mL (185.5 mM) Water: <1 mg/mL

Appearance: Solid Power

Shelf Life: 1.0 years
Description Tasisulam, also known as LY573636, is an acyl-sulfonamide with potential antineoplastic activity. Selectively toxic towards tumor cells, tasisulam appears to induce tumor cell apoptosis by a mitochondrial-targeted mechanism involving the loss of mitochondrial membrane potential and induction of reactive oxygen species (ROS). In combination with an angiogenesis inhibitor, this agent may exhibit synergistic antiangiogenic activity.