PCBP2 Monoclonal Antibody + Cell Lysate Kit
Applications
Reactivity
| Overview | |
| Catalog # | bsm-90020R |
| Product Name | PCBP2 Monoclonal Antibody + Cell Lysate Kit |
| Applications | WB, FCM, IC |
| Specificity | Knockdown Validated |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | A synthesized peptide derived from human PCBP2 |
| Immunogen Range | 257-300/365 |
| Clonality | Monoclonal |
| Clone # | 23GB2110 |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Affinity Purified |
| Storage Buffer | Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide. |
| Storage Condition | -20 °C |
| Target | |
| Gene ID | 5094 |
| Swiss Prot | Q15366 |
| Synonyms | PCBP2; Poly(RC) Binding Protein 2; Poly(RC)-Binding Protein 2; HNRNPE2; HNRPE2; Heterogeneous Nuclear Ribonucleoprotein E2; Heterogenous Nuclear Ribonucleoprotein E2; Alpha-CP2; HnRNP-E2; HnRNP E2; Epididymis Secretory Sperm Binding Protein; HNRNP-E2 |
| Background | Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Acts as a negative regulator of antiviral signaling. Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation. Together with PCBP1, required for erythropoiesis, possibly by regulating mRNA splicing (By similarity). Cell Line: HeLa Knockdown technology: shRNA Knockdown |
| Application Dilution | |
| WB | : 1:1000-1:5000 |
| FCM | FCM: 1:2000 |
| IC | IC: 1:1000 |
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