GAD65 Antibody Blocking Peptide
OVERVIEW | |
CATALOG # | BS-0400P |
PRODUCT NAME |
GAD65 Antibody Blocking Peptide
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CONJUGATION | Unconjugated |
SOURCE | Synthetic peptide derived from human GAD65 |
PURIFICATION: | Purified by HPLC/MS. |
STORAGE |
Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
TARGET | |
ACCESSION |
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UNIPROT |
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BACKGROUND |
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008] |