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TNF-alpha (1F6) Monoclonal Antibody, APC-Cy5.5 Conjugated

Applications

  • WB
  • IF(IHC-P)

Reactivity

  • Human
  • Mouse
Overview
Catalog # bsm-0387M-APC-Cy5.5
Product Name TNF-alpha (1F6) Monoclonal Antibody, APC-Cy5.5 Conjugated
Applications WB, IF(IHC-P)
Specificity This antibody is produced using full length recombinant TNF-alpha protein.
Reactivity Human, Mouse
Specifications
Conjugation APC-Cy5.5
Host Mouse
Source This antibody is produced using full length recombinant human TNF-alpha.
Immunogen Range 77-233/233
Clonality Monoclonal
Clone # 1F6
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein G.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 7124
Swiss Prot P01375
Subcellular location Secreted, Membrane bound
Synonyms DIF; TNFA; TNFSF2; TNF-alpha; Tumor necrosis factor; Cachectin; Tumor necrosis factor ligand superfamily member 2; TNF-a; TNF
Background Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200