Overview |
bs-9891R-BF488 |
NDST1 Polyclonal Antibody, AbBy Fluor® 488 Conjugated |
WB, IF(IHC-P) |
Human |
Specifications |
AbBy Fluor® 488 |
Rabbit |
KLH conjugated synthetic peptide derived from human NDST1 |
781-882/882 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
3340 |
[Heparan sulfate]-glucosamine N-sulfotransferase 1; Bunctional heparan sulfate N-deacetylase/N-sulfotransferase 1; Glucosaminyl N-deacetylase/N-sulfotransferase 1; Heparan sulfate N-deacetylase 1; Heparan sulfate N-sulfotransferase 1; HSNST 1; HSNST-1; HSST; HSST1; N-heparan sulfate sulfotransferase 1; N-HSST 1; NDST-1; Ndst1; NDST1_HUMAN. |
Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |