RFESD Polyclonal Antibody, HRP Conjugated
Applications
Reactivity
Predicted Reactivity
Overview | |
Catalog # | bs-8496R-HRP |
Product Name | RFESD Polyclonal Antibody, HRP Conjugated |
Applications | WB, ELISA, IHC-P, IHC-F |
Reactivity | Rat |
Predicted Reactivity | Human, Mouse |
Specifications | |
Conjugation | HRP |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human RFESD |
Immunogen Range | 51-157/157 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Gene ID | 317671 |
Subcellular location | Nucleus |
Synonyms | Rieske Fe S domain containing; Rieske domain containing protein; RFESD_HUMAN. |
Background | RFESD, also known as Rieske domain-containing protein, is a 157 amino acid protein that binds one 2Fe-2S cluster per subunit. Involved in metal ion binding, RFESD contains one Rieske domain. The RFESD gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 5q15. Chromosome 5 makes up approximately 6% of the human genome and contains 181 million base pairs, which encode 1,000 genes. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is caused by insertions or deletions within the TCOF1 gene and is also associated with chromosome 5. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
Application Dilution | |
WB | 1:300-5000 |
ELISA | 1:500-1000 |
IHC-P | 1:200-400 |
IHC-F | 1:100-500 |