| Overview |
| bs-8443R-PE-Cy5 |
| Lin28A/B Polyclonal Antibody, PE-Cy5 Conjugated |
| WB |
| This antibody is produced using synthetic peptide that falls within the range of 90-120 amino acids of human Lin28A. Due to 92% sequence similarity, this antibody may cross react with Lin28B. |
| Human, Mouse, Rat |
| Cow, Sheep, Pig, Horse, Rabbit |
| Specifications |
| PE-Cy5 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Lin28A |
| 75-180/209 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 79727, 389421 |
| 9H9Z2, Q6ZN17 |
| Cytoplasm, Nucleus |
| Protein lin-28 homolog A; LIN28A; Lin-28A; Zinc finger CCHC domain-containing protein 1; CSDD1; LIN28; ZCCHC1; Protein lin-28 homolog B; LIN28B; Lin-28B; CSDD2 |
| LIN-28 is a highly conserved, RNA-binding, cytoplasmic protein. It consists of a cold shock domain and retroviral-type (CCHC) zinc finger motifs that were first identified in Caenorhabditis elegans. LIN-28 controls the timing of events during embryonic development and is readily expressed in embryos, embryonic stem cells and embryonal carcinoma cells. The presence of LIN-28 persists in some adult tissues including cardiac and skeletal muscle. In differentiating myoblasts, LIN-28 increases protein synthesis efficiency and binds to the growth and differentiation factor IGF-II. |
| Application Dilution |
| WB |
1:300-5000 |
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