| Overview |
| bs-8034R-PE |
| COMMD1 Polyclonal Antibody, PE Conjugated |
| WB |
| Mouse |
| Human, Rat, Cow, Sheep, Horse, Rabbit |
| Specifications |
| PE |
| Rabbit |
| KLH conjugated synthetic peptide derived from human COMMD1/MURR1 |
| 95-190/190 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 150684 |
| Cytoplasm, Nucleus |
| C2orf5; COMD1; COMD1_HUMAN; COMM domain-containing protein 1; COMMD1; copper metabolism domain containing 1; MGC27155; MURR1; Protein Murr1. |
| Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF-kappa-B activity. Down-regulates SOD1 activity by interfering with its homodimerization. Plays a role in copper ion homeostasis. Can bind one copper ion per monomer. May function to facilitate biliary copper excretion within hepatocytes.Tissue specificity:Ubiquitous. Highest expression in the liver, with lower expression in brain, lung, placenta, pancreas, small intestine, heart, skeletal muscle, kidney and placenta. |
| Application Dilution |
| WB |
1:300-5000 |
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