| Overview |
| bs-7057R-PE |
| Glucokinase regulatory protein Antibody, PE Conjugated |
| WB |
| Rat |
| Human, Mouse, Dog, Pig, Horse, Rabbit |
| Specifications |
| PE |
| Rabbit |
| KLH conjugated synthetic peptide derived from human GCKR |
| 121-220/625 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 2646 |
| Q14397 |
| Nucleus |
| GKRP; FGQTL5; Glucokinase regulatory protein; Glucokinase regulator; GCKR |
| Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity. |
| Application Dilution |
| WB |
1:300-5000 |
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