| Overview |
| bs-6077R-PE |
| NIT1 Polyclonal Antibody, PE Conjugated |
| WB |
| Human, Mouse, Rat, Dog, Horse, Rabbit |
| Specifications |
| PE |
| Rabbit |
| KLH conjugated synthetic peptide derived from human NIT1 |
| 111-210/327 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 4817 |
| Cytoplasm |
| NIT1; NIT1_HUMAN; Nitrilase 1; Nitrilase homolog 1. |
| Play a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. it is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2. |
| Application Dilution |
| WB |
1:300-5000 |
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