| Overview |
| bs-5811R-PE |
| NUAK2 Polyclonal Antibody, PE Conjugated |
| WB |
| Human, Mouse |
| Rat, Dog, Cow, Rabbit |
| Specifications |
| PE |
| Rabbit |
| KLH conjugated synthetic peptide derived from human NUAK2 |
| 31-130/628 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 81788 |
| Q9H093 |
| Cytoplasm, Nucleus |
| SNARK; NUAK family SNF1-like kinase 2; Omphalocele kinase 2; SNF1/AMP kinase-related kinase; NUAK2; OMPHK2 |
| Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1. |
| Application Dilution |
| WB |
1:300-5000 |
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