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Sin3b Polyclonal Antibody, PE Conjugated

Applications

  • WB

Reactivity

  • Human

Predicted Reactivity

  • Mouse
  • Rat
  • Dog
  • Cow
  • Sheep
  • Horse
  • Chicken
Overview
Catalog # bs-4215R-PE
Product Name Sin3b Polyclonal Antibody, PE Conjugated
Applications WB
Reactivity Human
Predicted Reactivity Mouse, Rat, Dog, Cow, Sheep, Horse, Chicken
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Sin3b
Immunogen Range 261-360/1162
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 23309
Subcellular location Nucleus
Synonyms SIN3 homolog B transcription regulator; Transcriptional corepressor Sin3b; SIN3B_HUMAN.
Background Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
Application Dilution
WB 1:300-5000