Overview |
bs-3405R-PE-Cy3 |
PTPN11 (Tyr584) Polyclonal Antibody, PE-Cy3 Conjugated |
WB |
This phosphorylation site is homologous across the listed cross reactive species. |
Mouse, Rat |
Human, Horse, Chicken |
Specifications |
PE-Cy3 |
Rabbit |
KLH conjugated synthetic phosphopeptide derived from human PTPN11 around the phosphorylation site of Tyr584 |
Tyr584 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
5781 |
Q06124 |
Cytoplasm |
CFC; NS1; SHP2; BPTP3; PTP2C; PTP-1D; SH-PTP2; SH-PTP3; Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C; PTP-2C; SHP-2; PTPN11; SHPTP2 |
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity. |
Application Dilution |
WB |
1:300-5000 |