Overview |
bs-18727R-Biotin |
MCM-BP Polyclonal Antibody, Biotin Conjugated |
IHC-P |
Rat |
Human, Mouse, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit |
Specifications |
Biotin |
Rabbit |
KLH conjugated synthetic peptide derived from human MCM-BP |
551-642/642 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
79892 |
Q9BTE3 |
Nucleus |
C10orf119 ; chromosome 10 open reading frame 119 ; MCM-binding protein ; MCM-BP ; mcmbp ; MCMBP_HUMAN ; Mini-chromosome maintenance complex-binding protein ; Minichromosome maintenance complex binding protein. |
Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion. |
Application Dilution |
IHC-P |
1:200-400 |